Nordic MuBio

Sphingomyelin Phosphodiesterase 3

Product Code:
 
EXA-X2287B
Product Group:
 
Peptides
Supplier:
 
Nordic MuBio
Host Type:
 
Rabbit
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Ship at ambient temperature freeze upon arrival
Storage:
 
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
 

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CodeSizePrice
EXA-X2287B50 ug£162.00
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Further Information

Applications Description:
For use with Sphingomyelin Phosphodiesterase 3 polyclonal antibodies (Cat. No. X2359P & X2360P).
Background:
Sphingomyelin phosphodiesterase 3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these two cellular events independently. It also hydrolyzes sphingosylphosphocholine. Sphingomyelin phosphodiesterase 3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It likely acts as a regulator of postnatal development and participates in bone and dentin mineralization. It is activated by unsaturated fatty acids and phosphatidylserine. it is predominantly expressed in the brain.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Concentration:
See vial for concentration
Formulation:
Provided as solution in phosphate buffered saline
Functional Analysis:
Western Blotting
Product Form:
Unconjugated
Product Stability:
Products are stable for one year from purchase when stored properly
Synonyms:
nSMase2; Neutral sphingomyelinase 2; EC 3.1.4.12
UniProt:
Q9NY59